{"product_id":"epigenetics-and-gene-expression-in-cancer-inflammatory-and-immune-diseases","title":"Epigenetics and Gene Expression in Cancer, Inflammatory and Immune Diseases","description":"\u003cdiv id=\"bookDescription_feature_div\" class=\"celwidget\" data-feature-name=\"bookDescription\" data-csa-c-type=\"widget\" data-csa-c-content-id=\"bookDescription\" data-csa-c-slot-id=\"bookDescription_feature_div\" data-csa-c-asin=\"0993745598\" data-csa-c-is-in-initial-active-row=\"false\" data-csa-c-id=\"7y9w7h-rgk3d4-2xixgp-6jetc1\" data-cel-widget=\"bookDescription_feature_div\"\u003e\n\u003cdiv data-a-expander-name=\"book_description_expander\" data-a-expander-collapsed-height=\"280\" class=\"a-expander-collapsed-height a-row a-expander-container a-spacing-base a-expander-partial-collapse-container\"\u003e\n\u003cdiv aria-expanded=\"false\" class=\"a-expander-content a-expander-partial-collapse-content\"\u003e\n\u003cdiv data-cel-widget=\"bookDescription_feature_div\" data-csa-c-id=\"3xu427-hdulpm-xey1d9-kajk0v\" data-csa-c-is-in-initial-active-row=\"false\" data-csa-c-asin=\"1975136373\" data-csa-c-slot-id=\"bookDescription_feature_div\" data-csa-c-content-id=\"bookDescription\" data-csa-c-type=\"widget\" data-feature-name=\"bookDescription\" class=\"celwidget\" id=\"bookDescription_feature_div\"\u003e\n\u003cdiv class=\"a-expander-collapsed-height a-row a-expander-container a-spacing-base a-expander-partial-collapse-container\" data-a-expander-collapsed-height=\"280\" data-a-expander-name=\"book_description_expander\"\u003e\n\u003cdiv class=\"a-expander-content a-expander-partial-collapse-content\" aria-expanded=\"false\"\u003e\n\u003cdiv class=\"c-book-section\"\u003e\n\u003csection data-title=\"book-toc\"\u003e\n\u003cp\u003eThis practical collection examines methodologies originating from the benefits of genome-wide approaches to studying epigenetics, which has opened the emerging field of epigenomics. Focusing on the areas of cancer, inflammatory and autoimmune disorders, chapters discuss three main components of the epigenome and their role in the regulation of gene expression and present a detailed method section specific to studying each component, including data analyses, troubleshooting, and feasibility in different experimental settings. The main topics are high-throughput and targeted methods for DNA methylation analysis, nucleosome position mapping, studying epigenetic effects of gut microbiota, optical imaging for detection of epigenetic aberrations in living cells, methods for microRNA, and histone code profiling. Written for the Methods in Pharmacology and Toxicology series, the book includes the kind of detail and implementation advice to encourage success in the lab. \u003cbr\u003eAuthoritative and easily applicable, Epigenetics and Gene Expression in Cancer, Inflammatory and Immune Diseases aims to provide pharmacologists, molecular biologists, bioinformaticians, and toxicologists with a vital background on epigenetics and state-of-the-art techniques in epigenomics.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTable of contents (11 protocols)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePages i-xii\u003c\/p\u003e\n\u003cp\u003eHigh-Throughput Techniques for DNA Methylation Profiling\u003cbr\u003eSophie Petropoulos, David Cheishvili, Moshe Szyf\u003cbr\u003ePages 1-15\u003c\/p\u003e\n\u003cp\u003eReduced Representation Bisulfite Sequencing (RRBS) and Cell Sorting Prior to DNA Methylation Analysis in Psychiatric Disorders\u003cbr\u003eWilfred C. de Vega, Atif Hussain, Patrick O. McGowan\u003cbr\u003ePages 17-32\u003c\/p\u003e\n\u003cp\u003eTargeted DNA Methylation Analysis Methods\u003cbr\u003eDavid Cheishvili, Sophie Petropoulos, Steffan Christiansen, Moshe Szyf\u003cbr\u003ePages 33-50\u003c\/p\u003e\n\u003cp\u003eAnalyzing Targeted Nucleosome Position and Occupancy in Cancer, Obesity, and Diabetes\u003cbr\u003ePrasad P. Devarshi, Tara M. Henagan\u003cbr\u003ePages 51-62\u003c\/p\u003e\n\u003cp\u003eSynthesis and Application of Cell-Permeable Metabolites for Modulating Chromatin Modifications Regulated by α-Ketoglutarate-Dependent Enzymes\u003cbr\u003eHunter T. Balduf, Antonella Pepe, Ann L. Kirchmaier\u003cbr\u003ePages 63-79\u003c\/p\u003e\n\u003cp\u003eHigh-Throughput Screening of Small Molecule Transcriptional Regulators in Embryonic Stem Cells Using qRT-PCR\u003cbr\u003eEmily C. Dykhuizen, Leigh C. Carmody, Nicola J. Tolliday\u003cbr\u003ePages 81-95\u003c\/p\u003e\n\u003cp\u003eMethods for MicroRNA Profiling in Cancer\u003cbr\u003eSushuma Yarlagadda, Anusha Thota, Ruchi Bansal, Jason Kwon, Murray Korc, Janaiah Kota\u003cbr\u003ePages 97-113\u003c\/p\u003e\n\u003cp\u003eMicrobiota and Epigenetic Regulation of Inflammatory Mediators\u003cbr\u003eMarlene Remely, Heidrun Karlic, Irene Rebhan, Martina Greunz, Alexander G. Haslberger\u003cbr\u003ePages 115-134\u003c\/p\u003e\n\u003cp\u003eOptical Microscopy and Spectroscopy for Epigenetic Modifications in Single Living Cells\u003cbr\u003eYi Cui, Joseph Irudayaraj\u003cbr\u003ePages 135-154\u003c\/p\u003e\n\u003cp\u003eMicroRNAs in Therapy and Toxicity\u003cbr\u003eDavid J. MacEwan, Niraj M. Shah, Daniel J. Antoine\u003cbr\u003ePages 155-167\u003c\/p\u003e\n\u003cp\u003eGenetics and Epigenetics of Multiple Sclerosis\u003cbr\u003eBorut Peterlin, Ales Maver, Vidmar Lovro, Luca Lovrečić\u003cbr\u003ePages 169-192\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c\/section\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cb\u003eBOOKREAD™ 5-STEP SATISFACTION GUARANTEE\u003c\/b\u003e\u003c\/strong\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003e1. No Risk, 30-Day Money-Back Guarantee. \u003cbr\u003e2. instant download. No surprises or hidden fees.\u003cbr\u003e3. Safe Payments via Credit\/Debit Card or PayPal® \u003cbr\u003e4. McAfee™ and SSL secured shopping cart.\u003cbr\u003e5. lifetime customer support.\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"My Store","offers":[{"title":"PDF","offer_id":56778117316939,"sku":null,"price":29.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1031\/1204\/8971\/files\/978-1-4939-6743-8.webp?v=1773316357","url":"https:\/\/bookread.io\/products\/epigenetics-and-gene-expression-in-cancer-inflammatory-and-immune-diseases","provider":"bookread","version":"1.0","type":"link"}