A Review on Diverse Neurological Disorders Pathophysiology, Molecular Mechanisms, and Therapeutics

A Review of Diverse Neurological Disorders: Pathophysiology, Molecular Mechanisms, and Therapeutics offers an unparalleled compilation of the current understanding of neurodegenerative disorders. This book investigates the origins of mental disorders, encompassing bacterial and fungal invasions, viral assaults, and genetic predispositions, providing readers with a thorough grasp of the neurological landscape. Each chapter dissects the intricacies of these incapacitating conditions, ranging from the pathogenesis of central nervous system tuberculosis to the involvement of endocannabinoids in rabies infection. Topics such as neuroinflammation, axonal pathology, and the intricate relationship between diet, gut microbiomes, and cognitive decline are also explored. This book conducts an extensive examination of neurodegeneration, incorporating discussions on the role of probiotics and natural bioactive compounds in preventing ailments such as Parkinson’s, Alzheimer’s, and amyotrophic lateral sclerosis (ALS). With meticulous analyses of vitamins, micronutrients, antioxidants, and nutraceuticals, this work offers a roadmap for promoting neuroprotection. A Review of Diverse Neurological Disorders serves as a resource that not only reviews the current understanding but also lays the groundwork for future treatments and innovations.

Key features
Epidemiology of neurological disorders and pathogenesis.
Explores neuroinflammation, ligand-receptors binding, and neurodegeneration.
Discusses aging and associated disorders in the onset of neurological disorders.
Neuropharmacology and the protective role of bioactive compounds in neuroprotection.

Readership
Neurologists, Psychiatrists, and Psychologists from both academic and private settings health professionals, nurses and general practitioners, public health officials

Table of contents
Epidemiology and risk factors of mental disorders
Bacterial meningitis and neurological disorder
An overview on Helminthic brain infections in humans
Helminthic infections of the central nervous system
Pathogenesis and overview of central nervous system tuberculosis
Tuberculosis of central nervous system
An overview on tetanus, diphtheria, and diverse bacterial infections of the CNS
Tetanus, diphtheria and other bacterial infections of central nervous system
Pathogenesis and treatment of syphilis
Fungal infection of central nervous system
An overview on the fungal infections of the nervous system
Acute viral encephalitis, meningitis, and cerebral malaria
Neurological complications of COVID-19 infections
Genetic addiction risk analysis for “Preaddiction Severity Index” (PAI): A neurobiological behavioral octupus
Addressing the role of endocannabinoid system in rabies infection and its potential for modulation
Pathogenesis and Treatment of Rabies
An overview of pathophysiology and therapeutic approaches of Alzheimer’s disease and Parkinson’s disease
Ataxia and motor neuron diseases
Multiple system atrophy
Progressive supranuclear palsy
Epilepsy and Neurodegeneration
HIV/AIDS Neurological Disorders
Neurodegeneration and Motor Deficits
Neurodegeneration in autoimmune central nervous system infection
Inflammation and neurodegeneration in multiple sclerosis
Autophagy and mitophagy in amyotrophic lateral sclerosis
Excitation-inhibition balance in diseases of the brain: Role of NMDA and GABA receptors
Nutraceuticals for the prevention of stroke and cerebrovascular injury: An overview
HIV infection, type 1 interferons, and immune competence: Correlating brain immunity to neurodegeneration
Neuroinflammation: Role of adhesion molecules and signaling networks in neurovascular systems
Influence of Axonal Pathology in Traumatic Brain Injury
Axonal Pathology in Traumatic Brain Injury: An Overview
Ocular neurodegenerative disorders
Stress-associated neurodegenerative disorders: A mechanistic exploration
Diverse stress and neurodegeneration: An overview
Neurodegenerative diseases and circadian rhythm dysfunction: A bidirectional nexus
Advancing age, nutraceuticals, and neuroprotection
Novel treatments for neurodegenerative disorders predominantly presenting in children and young adults
CNS drugs: Classification, characterization, and binding properties towards biomacromolecules
The role of gut microbiome in insomnia
Novel therapeutics for diverse neurological disorders
Elucidating the potential of natural bioactive compounds in neuroprotection
Vitamins, micronutrients, antioxidants, and nutraceuticals in neuroprotection: An overview
Olive oil and mediterranean diet: The importance of olive oil constituents, and mainly of its polyphenols, in human health - The redox system - Xenohormesis hypothesis
Probiotics protect against progressive deterioration of motor functions and Parkinson’s disease
Neuroprotective abilities of vitamins, micronutrients, antioxidants, and nutraceuticals
Nutraceuticals and Natural Products in the treatment of neurological disorders
Unprecedented prospects as forthcoming drug targets: New boulevard in the cure and treatment of neurodegenerative disorders
The Threats and Therapeutics of Neurodegenerative Disorders: A Commentary
Review quotes
"...covers in detail the pathophysiology of neurodegenerative conditions and the current state of evidence for natural treatments for neurodegenerative conditions. [A] detailed Review of the pathophysiology of neuro degenerative conditions like Alzheimer’s, amyotrophic lateral sclerosis, and Parkinson’s disease. [C]overs microbiome and other natural treatments and their role in neuro degenerative conditions.....[And] the current research on pathophysiology of neurodegenerative conditions....One of the unique features of this book is the focus on natural treatments for these conditions....[U]nique for those interested in neurodegenerative conditions and natural therapies."—©Doody’s Review Service, 2024, Sridhara S Yaddanapudi, MD (Thomas Jefferson University)
About the editors
RC

Rameshwar Nath Chaurasia
Rameshwar Nath Chaurasia MBBS, MD, DM, MAMS received his D.M. in Neurology in 2009 from King George Medical University, Lucknow, India. He did his MBBS and M.D.(Medicine) from Institute of Medical Sciences, Banaras Hindu University, Varanasi, India. At present he is Professor & Head in the Department of Neurology, Institute of Medical Sciences, Banaras Hindu University, Varanasi. He served in the University at various administrative posts like Student Advisor, Anti Ragging Committee of University team, Deputy Chief Proctor etc.,He also served as founder Nodal officer of Ayushman Bharat Yojana (Biggest Health Scheme Yojana in World) in Sir Sundar Lal Hospital, I.M.S. BHU. He is Executive Council Member of AIIMS, Gorakhpur, Uttar Pradesh, India. Dr. Chaurasia received various awards/prizes from different Scientific/Non-scientific organizations and Societies for creating awareness about various neurological diseases in societies. His passion is to serve the needy people of India living in remote areas of different states of India by arranging health camps with the help of National Medicos Organization and Sewa Bharati of India. He also got teacher awards on teacher’s day from Governor and Chief Minister of Uttar Pradesh, India in 2017 and 2021 respectively. Dr R N Chaurasia has contributed >90 research papers in various peer reviewed national and international journals. He also contributed >10 book chapters in various books. He is reviewer of many national and international peer reviewed journals (>6). His main area of research is in the field of stroke, Epilepsy, cognitive science and CNS infections. He is member of various academic bodies in the field of neurosciences like Indian Academy of Neurology, Neurological Society of India, International Parkinson and Movement Disorder Society & American Academy of Neurology etc.
Affiliations and expertise
Department of Neurology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
SO

Sunny Ohia
Sunny Ohia is a Professor of Pharmacology in the College of Pharmacy and Health Sciences at Texas Southern University. Dr. Ohia has over 38 years of experience in higher education having served as a member of faculty in five universities in Canada and the United States. He holds other academic appointments as adjunct professor of ophthalmology and visual sciences at the University of Nebraska Medical Center, Omaha and as an adjunct professor of integrative biology and pharmacology at the University of Texas Health Sciences Center in Houston. Dr. Ohia is a Fellow of the Nigerian Academy of Science and a Fellow of the Association for Research in Vision and Ophthalmology. He's authored over 250 original papers, book chapters, books, and abstracts and, holds three U.S. and five international Patents for his scientific work.
Affiliations and expertise
Professor, College of Pharmacy and Health Sciences, Texas Southern University, Houston, TX, USA
DB

Debasis Bagchi
Debasis Bagchi earned his Ph.D. in Medicinal Chemistry in 1982 and is a Professor in the Department of Pharmacological and Pharmaceutical Sciences at the University of Houston College of Pharmacy. He also serves as Chief Scientific Officer at Cepham Research Center and holds adjunct faculty appointments. Previously, he was Senior Vice President of Research & Development at InterHealth Nutraceuticals (1998–2011) and later Director of Innovation and Clinical Affairs at Iovate Health Sciences (2011–2013).

Dr. Bagchi received the Master of the American College of Nutrition Award in 2010 and has held leadership roles including Past President of the American College of Nutrition and Past Chairman of the International Society of Nutraceuticals and Functional Foods. He contributes as an NIH peer reviewer and advisor to international health organizations.

A prolific scholar, he has authored over 320 peer-reviewed papers, 30 books, and holds 18 patents. He also serves on editorial boards of numerous scientific journals.

Affiliations and expertise
Professor, Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, USA; Chief Scientific Officer, Cepham Research Center, Piscataway, New Jersey; Adjunct Faculty, Texas Southern University, Houston, Texas, USA