This book highlights the potential applications of microbots for minimally invasive diagnosis of colorectal cancer (CRC), enhancing the accuracy of colonoscopy and improving drug delivery for more precise and effective treatments. The introductory chapter explores advanced CRC diagnostic and therapeutic approaches, from understanding the disease’s prevalence to assessing the limitations of invasive techniques. It further discusses non-invasive screening methods and state-of-the-art imaging technologies, paving the way for less intrusive and more accessible diagnostics. The book, in turn, reviews techniques to tailor microbots for specifically targeting cancer cells effectively and provides a comparative analysis with nanobots for their potential in cancer diagnostics and therapeutics. It explores the intersection of photodynamic therapy and microrobotic technology, shedding light on the future of cancer therapy. With a focus on clinical translation, this book provides insight into the future application of m
Key Features
- Explores the latest advancements in microbot applications in diagnosis and drug delivery in colorectal cancer
- Offers a comprehensive examination of colorectal cancer diagnostics, ranging from traditional colonoscopies to advanced imaging technologies
- Presents practical applications and the potential for clinical translation of microbots in diagnosing and treating colorectal cancer
- Examines the potential use of mobile microrobots in medical imaging and offers in vivo perspectives on colorectal cancer
- Discusses techniques for customizing microbots to effectively target cancer cells and provides a comparative analysis with nanobots
Table of Contents
Preface
About the Editors
Chapter 1 Non-Invasive Screening Techniques for Colorectal Cancer
Juan Anderson, Malcolm Lovett, Maya Saunders, Jayanta K. Das, and Madhumita Das
Chapter 2 Role of Computational Analysis in Early Diagnosis of Colorectal Cancer
Manab Mandal, Sourav Mazumdar, Narendra Nath Ghosh, Asoke P. Chattopadhyay, and Nabajyoti Baildya
Chapter 3 Targeted Drug Delivery: A Promising Future in the Diagnosis and Treatment of Colorectal Cancer
Sheena Mariam Thomas and Ramakrishnan Veerabathiran
Chapter 4 Limitations and Disadvantages of Invasive Techniques in Colorectal Cancer Diagnosis
Jayenth Jayachandran, Arunkumar Radhakrishnan, Shruthi Nagainallur Ravichandran, Surajit Pathak, and Antara Banerjee
Chapter 5 Artificial Exosomes: As Innovative Drug Carriers for Colorectal Cancer Treatment
Ravindran Jaganathan, Rajeswari Ravindran, Nur Aliaa Sorfina Binti Tajul Akmal, Lurdes Queimado, Gautham Chengizkhan, Mayilvanan Chinnaiyan, Vengatesh Ganapathy, Balaji Sadhasivam, Ravi Gor, and Ilangovan Ramachandran
Chapter 6 Medical Imaging of Gastrointestinal Diseases and Cancer Using Microbots
Chandrasudan Ramamurthy, Disha Kamath, Mrinalini Rajaraman, Sruthi R. Ravi Gor, Balaji Sadhasivam, N. Arul Jothi, and Satish Ramalingam
Chapter 7 3D Printed Biomedical Theranostic Microbots for Colorectal Cancer
Pavithra Velmurugan, Suresh Kumar Saravanan, Veni Subramanyam, and Haema Ganapathi
Chapter 8 Advances in Biohybrid Microbots in Colon Cancer Therapy
Girish Kanavi K., Gowrav Bharadwaj, Mythreyi R., Mutthuraj D., Kanthesh B. M., and Gobianand Kuppannan
Chapter 9 The Role of Magnetic Microbots in Colorectal Cancer
Arjun KR, Avipsa Hazra, Mythreyi R, Mutthuraj D, Kanthesh BM, and Umamaheshwari S
Chapter 10 In Vivo Perspective of Microrobots/Microbots in Colorectal Cancer
Ravi Gor, Lurdes Queimado, Vengatesh Ganapathy, Evan Floyd, Satish Ramalingam, Ilangovan Ramachandran, Sathish Sivaprakasam, and Balaji Sadhasivam
Chapter 11 Mechanism of Action of Microbots and Its Role in Cancer Diagnosis
Shrishti Madhan, Rohan Agnihotram, and Arikketh Devi
Chapter 12 Bio-Nanotechnology and Microbots: Applications in Colorectal Cancer
Bipin D. Lade and Ishfaq Ahmed
Chapter 13 Microrobots in Colorectal Cancer Diagnosis: Advancements and Applications
Sneha Pallatt, Ashiq Shibili, Sibin Nambidi, Samatha M Jain, Antara Banerjee, and Surajit Pathak
Index
Editor(s)
Biography
Dr. Surajit Pathak is currently working as a Professor at Chettinad Academy of Research and Education, Kelambakkam, Chennai. He received his Ph.D. in Zoology from the University of Kalyani, West Bengal, India, in 2007 and completed his post-doctoral training at the University of Linkoping, Sweden; the University of Padova, Italy; and the University of Alabama, USA. His current research focuses on cancer biology, stem cell biology, regenerative medicine, and microRNA. He has published more than 60 research articles in peer-reviewed journals and has received various research grants, including core research grants from SERB (DST) and DST Indo-Italy Bi-lateral research projects. He is an editorial board member of various respected journals.
Dr. Antara Banerjee is currently working as an Associate Professor at the Chettinad Academy of Research and Education, Kelambakkam, Chennai. Antara Banerjee completed her PhD in 2008 and pursued her post-doctoral research at the University of Padova, Italy, till 2012. Later, she joined as a senior research associate at the University of Linkoping, Sweden, until 2015. She has published more than 50 impactful peer-reviewed articles in International and National Journals. Her core expertise is in stem cell biology, regenerative medicine, and oncology. She has received numerous awards, including the DST SERB and ECR awards from the Government of India for the period 2018–2021.
